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550 - No such domain at this location

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We recently installed Exchange 2013 in coexistence with Exchange 2010 with the intention of migrating all of our users to Exchange 2013.  My problem is that the new mailbox servers are not sending email externally.  Our existing Exchange 2010 server is currently sending all of the mail.  When I add the new servers to the existing send connector users start receiving undelivered responses stating "550 no such domain at this location".  I've tried creating a new send connector but nothing I do seems to correct the issue.  We use a Barracuda Spam Filter and it doesn't even see the attempts to send mail from the 2013 servers.  

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