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550 5.4.1 Relay Access Denied from outbound mail from Exchange 2013 on-premise to EOP

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I have an Exchange 2013 hybrid infrastructure with Office 365 (tenant 15....)

Mail flow is working well between in cloud mailbox and on-premise mailbox.

I have set the Outbound connector on my on-premise server to route mail through EOP (FOPE) on office 365:

mail.messaging.microsoft.com.

I get this delivery report every time:

Submitted
4/22/2013 5:17 PM EXCHANGIX
The message was submitted to exchangix.franskaskolan.se.

Pending
4/22/2013 5:17 PM exchangix.franskaskolan.se
Message was received by exchangix.franskaskolan.se from EXCHANGIX.franskaskolan.se.

Failed
4/22/2013 5:17 PM exchangix.franskaskolan.se
A communication failure occurred during the delivery of this message.

[{LRT=};{LED=550 5.4.1 Relay Access Denied};{FQDN=};{IP=}]

I have activate for a while (FOPE) for my volume licenses users, but I want to use EOP on office 365 now.

thanks


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